Is there an advantage to using Macrobid instead of Macrodantin ? Macrobid takes this a step further by using the monohydrate salt form-all you need to know about this is that it is supposed to further decrease the chance of stomach upset. Only the macrocrystalline versions are still available. Medications containing nitrofurantoin were later reformulated with macrocrystals to slow absorption and decrease the effect on your stomach. Nitrofurantoin products were originally formulated as microcrystals, which came with the unwanted side effects of nausea and vomiting. Macrodantin is available as a capsule in three strengths: 25 mg, 50 mg, and 100 mg. How is Macrodantin ( nitrofurantoin macrocrystalline) available? Macrobid is available as a 100 mg capsule. How is Macrobid ( nitrofurantoin mono/macro ) available? The active ingredient in Macrodantin is nitrofurantion macrocrystalline (sometimes just referred to as nitrofurantoin)-which differs a little from the type of nitrofurantoin in Macrobid. Macrodantin, on the other hand, is typically taken 4 times daily. The active ingredient in Macrobid is nitrofurantoin monohydrate macrocrystals or nitrofurantoin mono/macro. Macrobid has its daily dosing schedule right in its name-it’s taken 2 times daily (sometimes abbreviated BID on a prescription: Macro BID).
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